Pharmaceuticals are enduring, active compounds that, when released into the natural surroundings, impact the equilibrium of ecosystems. The rising prevalence of drugs and their transformation byproducts in the surroundings has garnered increased attention. Numerous commonly prescribed medications, particularly analgesics and antimicrobial agents, are employed in quantities comparable to agricultural pesticides yet are not subjected to equivalent environmental risk assessments. The environmental destiny and actions of pharmaceuticals necessitate more investigation. People and veterinary medications and their substances are disseminated in the environment through many pathways. Drugs and their metabolites have been documented in underground and groundwater, potable water, particles, soil, wastewater, drainage waste, and animal tissues. The paper addresses concerns regarding the disposition and effects of medicines in the surroundings and in handling sewage, ecological toxicology, and risk assessment procedures.