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Volume 10 - No: 3

Harnessing CRISPR-Based Gene Drives for Ecological Restoration and Biodiversity Conservation in Aquatic Ecosystems

  • Dr.K. Madhura Assistant Professor, Senior Scale Information and Communication Technology, Manipal Institute of Technology, Mahe Bengaluru, India.
    madhura.k@manipal.edu
    https://orcid.org/0000-0002-0135-5773
  • Gulzat Ziyatbekova Department of Information Systems, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
    https://orcid.org/0000-0002-9290-6074
  • Sheuli Sen Professor, Principal, Teerthakar Parshvnath College of Nursing, Teerthakar Mahaveer University, Uttar Pradesh, India.
    sheulisen100@gmail.com
    https://orcid.org/0000-0002-0276-5918
  • Zhanar Kobenkulova Faculty of Construction Technologies, Infrastructure and Management, International Educational Corporation, Almaty Kazakhstan.
    janarkazgasa@mail.ru
    https://orcid.org/0000-0001-8093-728X
  • Ankit Punia Centre of Research Impact and Outcome, Chitkara University, Rajpura, Punjab, India
    ankit.punia.orp@chitkara.edu.in
    https://orcid.org/0009-0003-6508-2596
DOI: 10.28978/nesciences.1811169
Keywords: CRISPR, gene drives, biodiversity conservation, ecological restoration, aquatic ecosystems, genetic diversity, climate change.

Abstract

The loss of biodiversity all over the world due to climate change and ecosystem destruction requires new conservation strategies. CRISPR-based gene drives offer promising opportunities for ecological restoration and biodiversity conservation, especially in aquatic environments, have a bright future. Gene drives are based on CRISPR / Cas9 technology that makes it possible to change the genetic characteristics of wild populations, which would contribute to resilience against various environmental stressors, including climate change, invasive species, and disease. CRISPR gene drives can help restore the genetic diversity of endangered species, as it allows beneficial characteristics to spread through populations and aid in ensuring the control of invasive species that endanger native ecosystems. Nevertheless, the introduction of gene drive technologies creates major ethical, ecological, and governance issues. These are the possibility of an unwanted ecological impact, problems with the transboundary flow of modified organisms, and the presence of strong regulatory frameworks to provide responsible use. This paper will examine the possible use of CRISPR-based gene drives in restoring aquatic ecosystems, in terms of their capacity to increase species adaptability, decrease extinction pressures, and recover ecosystem homeostasis. The results provide significant statistical insights, demonstrating that CRISPR-based gene drives can achieve an 85% allele frequency within just five generations and reduce invasive Asian carp populations by 60% within three generations. The regulatory and ethical factors are also addressed, and it is reasonable to note that it is important to collaborate globally and closely monitor the situation in order to reduce risks. The bright future of CRISPR-based gene drives implies new research and development to overcome the challenges and ensure that their safe and efficient use in conservation tactics.

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Date

December 2025

Page Number

900-911