Volume 8 - No: 2
The Genotoxic Damage in Cyprinus carpio Exposed to Abamectin
- Funda Turan
Iskenderun Technical University, Faculty of Marine Science and Technology, Hatay, Türkiye.
turanfunda@yahoo.com
- Ayşegül Ergenler
Iskenderun Technical University, Faculty of Marine Science and Technology, Hatay, Türkiye.
Keywords: Abamectin, DNA damage, pesticide, comet assay
Abstract
The pesticide abamectin, which is often used in agriculture, poses a threat to aquatic animals.
Though its toxicity to fish has not yet been fully understood. In this study, we used the comet assay
to examine the effects of being subjected to various dosages of abamectin on the genotoxic impact
of abamectin in Cyprinus carpio. During 10 days, common carp were exposed to three different
doses of abamectin (0.3, 0.6, and 0.9 mg L-1
) based on previously discovered levels in aquatic
environments. Toward the completion of the investigation, the Comet assay was used to assess the
damage frequency (%), Arbitrary unit (%), and Genetic damage index (%) in carp gill and liver
cells. The greatest damage frequencies of % 74.333±0.577 and % 70.333±2.082 were significantly
found in the 0.9 mg L-1
group in the gill and liver cells, respectively (P<0.001). Our results showed
a considerable increase in DNA strand breaks in C. carpio after exposure to abamectin, suggesting
the pesticide's capacity to be genotoxic to fish.