This field experiment was conducted to examine the effect of Spent Mushroom, biological and mineral fertilizers and their effect on some plant indicators in a field planted with Zea Mays L. at harvesting. The results of the experiment indicated that the use of Spent Mushroom, the application of mineral fertilizer at different levels and both types of biofertilizer, which Mentioned like (O, B and M) resulted in a significant increase in Some plant growth indicators. The highest average plant height was 297.3 (cm) for the treatment (O1B1M3), for dry weight 11.97 (mg ha-1) for treatment (O1B2M3), the grain yield was 11.32 (mg ha-1) for the treatment (O1B1M3), the biological yield was 26.37 (mg ha-1) for the treatment (O1B1M3) and the chlorophyll content was 114.30 (SPAD). Compared to the comparison treatment. It can be concluded from the above that the use of Spent Mushroom farm waste as organic fertilizer, as well as biological of both types and mineral fertilizers, and despite the varying results of the fertilizers used, they led to plant growth indicators which is reflected in their quality.