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Volume 10 - No: 2

The Potential Effect of Aqueous Extract of Cloves on Some Physiological and Immunological Parameters in Induced Diabetic Rats

  • Majeed Hameed Nawar Department of Plant Protection, Agriculture Engineering Sciences College, University of Baghdad, Baghdad, Iraq.
    majeed.hameed@coagri.uobaghdad.edu.iq
    https://orcid.org/0009-0005-7659-6263
  • Salah M.M. Al Chalabi Biotechnology Research Center, Al-Nahrain University, Iraq.
    salahchalabi63@gmail.com
    https://orcid.org/0000-0002-1707-7106
  • Rashaa F. Abdul-Lattif University of Baghdad, College of Education IBN Al-Haitham, Baghdad, Iraq.
    rasha.f.al@ihcoedu.uobaghdad.edu.iq
    https://orcid.org/0000-0002-6261-9875
DOI: 10.28978/nesciences.1733981
Keywords: Cloves, diabetic, LDH, CRP, SOD, CAT, MDA

Abstract

The purpose of this study was to investigate the effect of clove aqueous extract on various physiological and immunological markers using a diabetic rat model. Thirty rats participated in the study and were split into three groups: a normal negative-controlled group, a positive control group with diabetes, and a diabetes-induced group that was given a dosage of clove water extract. There is a list of some physiological and immunological parameters which have been measured: blood sugar level, interleukins 1 and 6, TNF, LDH, CRP, SOD, CAT, MDA, total and differential count of white blood cells. According to the research, the animals within the diabetes treatment group that received aqueous extracts from the clove plant had noticeably lower blood sugar levels than the animals in the untreated diabetes treatment group. The results also showed that the group that got induced diabetes but no therapy had significantly higher levels of TNF, lactate dehydrogenase (LDH), or Lac CRP, Superoxide dismutase (SOD), Malondialdehyde (MDA), CAT, and the total number of white blood cells than both the control group as well as the group that receiving diabetic medication. Regarding the aqueous extract of cloves.

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Date

August 2025

Page Number

239-254